South Carolina Department of Public Safety officials said there were five road deaths reported over the weekend.
Officials said all of the deaths occurred on U.S. routes, S.C. roads and secondary roads.
In two of the deaths, officials said a seat belt was not used. Pedestrians accounted for two of the deaths, and another was an unhelmeted motorcyclist.
As of Sunday, 442 people have died on state highways, compared to 446 highway deaths during the same time period in 2015. Of the 298 motor-vehicle occupants who have died in 2016, 146 were not wearing seat belts.
Fifty-five pedestrians have been killed compared to 53 during the same time period in 2015. Fifty-nine motorcyclists have been killed compared to sixty-three this time in 2015. Eleven bicyclists have died in 2016 compared to nine this time last year.