Virginia (0-3) at North Carolina (3-1), noon
This is the 114th meeting in the series. The first matchup was in 1892 and the teams have met annually since 1919. The Cavs have won three in a row over the Tar Heels. This is the ACC opener for Virginia, while North Carolina already has lost a league game. Another loss would all but eliminate the Tar Heels from the ACC Coastal Division title race. North Carolina 28-13
Virginia Tech (3-1) at Duke (2-2), noon
Virginia Tech is coming off back-to-back victories at home over Nebraska and Miami, and Duke is a step down in competition. Still, the Hokies struggled to put away the Blue Devils last season and cannot afford too big a letdown. Virginia Tech 23-10
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Florida State (2-2) at Boston College (3-1), 3:30 p.m.
Florida State's offensive line was whipped last week by South Florida's defensive line, and Boston College's defensive ends have to worry FSU's offensive coaches. FSU's pass defense has been atrocious, but BC's pass offense is mediocre. Florida State 23-17
N.C. State (3-1) at Wake Forest (2-2), 3:30 p.m.
In its two losses, Wake has committed seven turnovers; in its two wins, it has committed zero. This is N.C. State's ACC opener; Wake has one Atlantic Division loss and cannot afford another. N.C. State 27-24
Oklahoma (2-1) at Miami (2-1), 8 p.m.
This is a "prove it game" for both teams. Oklahoma has won its past two against less-than-stellar competition after falling to BYU in the opener. Miami looked sharp in winning its first two games, then looked mediocre in falling last week at Virginia Tech. Both offensive lines have something to prove. Oklahoma 20-17
Alabama (4-0) at Kentucky (2-1), 12:20 p.m.
Alabama leads this "rivalry" 34-2-1; UK's wins came in 1922 and 1997. This is the Tide's first true road game of the season, and they also play at Ole Miss next week. Alabama 38-10
LSU (4-0) at Georgia (3-1), 3:30 p.m.
This is the start of a huge stretch for LSU, which also plays Florida, Auburn and Alabama over the next five weeks. Georgia, meanwhile, will not play at home again until Nov. 7. Georgia is the only SEC team that LSU coach Les Miles has not beat. Georgia 24-20
Ole Miss (2-1) at Vanderbilt (2-2), 7 p.m.
After last week's loss at South Carolina, Ole Miss is in desperation mode. Vandy beat the Rebels in Oxford last season, but Ole Miss has won 12 of the past 16 in the series. Vandy's offense will not have much success against Ole Miss' defense. But can the Ole Miss offense get untracked? Ole Miss 21-10
Georgia Tech (3-1) at Mississippi State (2-2), 7:30 p.m.
This marks the first time Georgia Tech has played in the state of Mississippi. With the arrival of coach Dan Mullen, Mississippi State has an offensive pulse this season. Can the Bulldogs stifle Tech's triple-option offense? Georgia Tech 31-21
Auburn (4-0) at Tennessee (2-2), 7:45 p.m.
A battle of first-year coaches in the SEC. Auburn's Gene Chizik has a solid offense but a mediocre defense. Tennessee's Lane Kiffin has a solid defense but a pitiful offense. Auburn has won four in a row in the series, including a 14-12 victory last season that set offensive football back about two decades. Auburn 24-20