North at C.A. Johnson (Bolden Stadium): North carries 17-game losing streak into game.
Pick: C.A. Johnson
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A.C. Flora at Lugoff-Elgin: L-E eyes third win in a row; Falcons looking for first.
Pick: A.C. Flora
Airport at Gilbert: Indians have been a surprise and will have to play freshman QB next several weeks.
Batesburg-Leesville at Mid-Carolina: Panthers are 33-9 all-time against Rebels.
Camden at Cheraw: Bulldogs must defend the run better this week.
Dreher at River Bluff: Gators coming off back-to-back 21-17 losses.
Pick: River Bluff
Dutch Fork at Summerville: No. 1 Silver Foxes make second trip in a row to Lowcountry.
Pick: Dutch Fork
Fairfield Central vs. Ridge View (at Spirit Communications Park): Fourth different venue for Ridge View in unbeaten start to season.
Pick: Ridge View
Hammond at Ben Lippen: Falcons can make statement by stopping Skyhawks’ 27-game winning streak.
Heathwood Hall at Pinewood Prep: Pinewood has allowed 18 points over first three games.
Pick: Pinewood Prep
Irmo at Laurens: Yellow Jackets’ two losses by combined four points.
Keenan at White Knoll: Timberwolves come back strong after bye week.
Pick: White Knoll
Lamar at Eau Claire (Bolden Stadium): Silver Foxes have looked like Class As No. 1 team in first three games.
Laurence Manning at Cardinal Newman: Cardinals had extra week to get ready for LMA.
Pick: Laurence Manning
Lee Central at Columbia (Memorial Stadium): Stallions 2-0 against Midlands teams this year.
Pick: Lee Central
Lower Richland at Richland Northeast: Cavaliers coming off heart-breaking loss to Spring Valley.
Pick: Richland Northeast
Newberry at Chapin: All of Chapin’s games have been decided by three points.
North Augusta at Lexington: Wildcats look to break out of early-season funk.
Spring Valley at Sumter: Biggest test of season for unbeaten Spring Valley.
Timmonsville at North Central: Teams have split meetings over past two years.
Pick: North Central
Westwood at Blythewood: Battle for the Axe awaits between Richland 2 rivals
Last Week: 14-7