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A Columbia Walgreens store plans to close its doors. Here’s where and when

The Walgreens at 6500 Garners Ferry Road in Columbia, SC plans to close on Jan. 27, 2026.
The Walgreens at 6500 Garners Ferry Road in Columbia, SC plans to close on Jan. 27, 2026. chtrainor@thestate.com

A major pharmacy chain is set to close a Columbia store along a busy road.

Walgreens, which has thousands of stores across the U.S., plans to close the location at 6500 Garners Ferry Road on Jan. 27, 2026, according to a notice on the company’s website and signage posted on the front door of the store.

The sign on the front door of the Walgreens at 6500 Garners Ferry says the location — both the store and its pharmacy — will close for good at noon on Jan. 27. The sign noted that the location’s prescription files will be sent to the Walgreens at 7801 Garners Ferry. That’s about three miles south of the location at 6500 Garners Ferry.

A sign at the Walgreens at 6500 Garners Ferry Road in Columbia notes the business will close in January.
A sign at the Walgreens at 6500 Garners Ferry Road in Columbia notes the business will close in January. Chris Trainor chtrainor@thestate.com

The Walgreens that is closing at 6500 Garners Ferry is in the midst of a high-traffic commercial corridor, directly across from the Dorn Veterans Affairs Medical Center. Numerous businesses are nearby including Target, Krispy Kreme, Sonic Drive-In and Barnes & Noble, among others.

Garners Ferry Road is one of the most high-traffic non-interstate roads in the Midlands, with more than 48,000 cars per day traveling the thoroughfare near the Dorn VA, according to state Department of Transportation statistics.

There are roughly 8,000 Walgreens stores in the U.S., per data website ScrapeHero.

This story was originally published December 18, 2025 at 5:00 AM.

Chris Trainor
The State
Chris Trainor is a retail reporter for The State and has been working for newspapers in South Carolina for more than 21 years, including previous stops at the (Greenwood) Index-Journal and the (Columbia) Free Times. He is the winner of a host of South Carolina Press Association awards, including honors in column writing, government beat reporting, profile writing, food writing, business beat reporting, election coverage, social media and more.
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