Clemson University

Clemson vs. Florida State: Kickoff time, TV channel, injury report, odds

Florida State quarterback Tommy Castellanos (1)
Florida State quarterback Tommy Castellanos (1) Getty Images

Clemson football faces an ACC rival at home on Saturday night.

Here’s your gameday guide as the struggling Tigers host Florida State.

Clemson vs. Florida State game, TV info

Clemson vs. Florida State Vegas odds

Clemson is favored by 1.5 points vs. Florida State, according to the VegasInsider.com consensus betting line. The point spread opened at Clemson -3.5 or Clemson -2.5 in most sportsbooks and has dropped slightly, as most bettors have picked FSU to cover.

Weather forecast for Clemson, SC

Clemson will see some fall weather and potential rain on Saturday night, per the Weather.com 10-day forecast. The forecast: Cloudy with light winds, occasional showers (50% chance of rain) and a low of 55 degrees.

The Duke Blue Devils defense swarm Antonio Williams #0 of the Clemson Tigers during the first half of their game last week.
The Duke Blue Devils defense swarm Antonio Williams #0 of the Clemson Tigers during the first half of their game last week. David Jensen Getty Images

Top storylines for the game

  • Clemson and Florida State both released their initial ACC availability reports Thursday night. There were no major surprises on Clemson’s list, but defensive tackle Vic Burley and offensive lineman Collin Sadler are both considered probable to play. Among FSU’s key injury notes: starting DE James Williams and co-starting LB Stefon Thompson are questionable, and rotational running back Roydell Williams is probable.
  • If Clemson loses to Florida State on Saturday, it will be their seventh-straight home loss to a power conference team. According to research from The Clemson Insider’s Will Vandervort, that has not happened since 1907-17, a 10-year period where Clemson football only played a couple home games a year. That was 108 years ago. Clemson’s six straight home losses to power conference teams (which dates back to 2024) are already its worst since losing six straight in 1970-71.
  • Florida State’s record isn’t great, but its offense is legit. FSU ranks No. 1 nationally with 510.5 yards of total offense per game; leads the country in plays of 30-plus yards (33) and plays of 40-plus yards (18); and is also top five nationally in plays of 50-plus and 60-plus yards. It’s worth noting FSU had two massive outputs in early blowout wins over East Texas A&M (FCS) and Kent State (Group of Five). Specifically against P4 teams, the Seminoles drop to No. 19 nationally in total offense and No. 30 in scoring offense. For Clemson’s struggling defense, gashed by SMU and Duke in its last two games, Florida State still presents a big challenge.
  • Losing to Florida State wouldn’t eliminate Clemson from bowl eligibility. It would put Clemson in a “zero room for error” situation, though. Sitting at 3-5 through eight games, the Tigers must win three of their last four games to reach six wins and qualify for a bowl (FSU, No. 14 Louisville, FCS Furman and South Carolina). Clemson, which is 2-5 against P4 opponents and has not beaten a P4 team that currently has a winning record, also must finish 2-1 against P4 teams. ESPN’s FPI says Clemson has a 37.9% chance of reaching six wins. Pro Football Focus is a bit more optimistic at 50%.
Clemson quarterback Cade Klubnik (2) vs. Duke on Nov. 1, 2025
Clemson quarterback Cade Klubnik (2) vs. Duke on Nov. 1, 2025 David Jensen Getty Images

Clemson vs. Florida State players to watch

Clemson QB Cade Klubnik: The senior is coming off his cleanest game of the year vs. Duke: a career-high 385 yards, two touchdown passes and no turnovers.

Clemson S Khalil Barnes: Barnes and the rest of the defensive backs need a major bounceback game after coverage busts allowed multiple long touchdowns vs. Duke.

Florida State QB Tommy Castellanos: The Boston College transfer leads the country in yards per completion (16.77) and will be one of the best rushing QBs Clemson faces this season (50.8 yards per game excluding sacks, six TDs).

Florida State DB Earl Little Jr.: Ballhawk who has recorded an interception in three straight games and also has 52 tackles and two forced fumbles.

Clemson 2025 football schedule

Listed with known kickoff times and TV channels

Clemson 2025 football depth chart

As of Nov. 3

Offense

QB: Cade Klubnik (Christopher Vizzina)

RB: Adam Randall (David Eziomume OR Gideon Davidson)

Outside WR: T.J. Moore (Cole Turner)

Outside WR: Tristan Smith OR Cole Turner

Slot WR: Antonio Williams (Tyler Brown)

TE: Olsen Patt-Henry (Josh Sapp OR Christian Bentancur)

LT: Tristan Leigh (Brayden Jacobs)

LG: Collin Sadler OR Harris Sewell (Ronan O’Connell)

C: Ryan Linthicum (Harris Sewell)

RG: Walker Parks OR Elyjah Thurmon (Ronan O’Connell)

RT: Blake Miller (Mason Wade)

Defense

DE: Will Heldt OR Jahiem Lawson

DT: DeMonte Capehart OR Stephiylan Green (Amare Adams)

DT: Peter Woods OR Stephiylan Green (Vic Burley)

DE: T.J. Parker (Cade Denhoff)

MLB: Sammy Brown (Jeremiah Alexander OR Dee Crayton)

WLB: Wade Woodaz (Kobe McCloud OR Dee Crayton)

CB: Avieon Terrell (Branden Strozier)

Tiger (nickel): Misun Kelley (Corian Gipson OR Noah Dixon)

Rover (SS): Khalil Barnes OR Ronan Hanafin (Tyler Venables)

FS: Ricardo Jones (Kylon Griffin)

CB: Ashton Hampton OR Jeadyn Lukus (Corian Gipson)

Special teams

PK: Nolan Hauser (Robert Gunn III)

P: Jack Smith (Robert Gunn III OR Will McCune)

KO: Robert Gunn III

LS (PK): Holden Caspersen

LS (P): Philip Florenzo

H: Clay Swinney

PR: Antonio Williams

KOR: Adam Randall

This story was originally published November 7, 2025 at 8:00 AM.

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Chapel Fowler
The State
Chapel Fowler, the NSMA’s 2024 South Carolina Sportswriter of the Year, has covered Clemson football and other topics for The State since summer 2022. His work’s also been honored by the Associated Press Sports Editors, the South Carolina Press Association and the North Carolina Press Association. He’s a Denver, N.C., native, a UNC-Chapel Hill alum and a pickup basketball enthusiast. Support my work with a digital subscription
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