Airport at Orangeburg-Wilkinson: Playoff rematch from last year, won by Airport.
Andrew Jackson at North Central: Cedrick Cunningham looking for another highlight-reel run.
Pick: North Central
Barnwell at Swansea: Swansea has lost two in a row, while Barnwell has yet to lose.
Ben Lippen at Porter-Gaud: Falcons coming off big win over Hammond, will get tough test at P-G.
Pick: Ben Lippen
Blythewood at Irmo: Bengals have gotten things going following loss to Ridge View.
Brookland-Cayce at Chapin: Big plays have been the key for B-C this season.
C.A. Johnson at Bethune-Bowman: CAJ coming off first win, Bethune-Bowman first loss.
Chester at Lower Richland: Diamond Hornets have struggled in nonregion play.
Columbia at Keenan (Bolden Stadium): Keenan has won three in a row in series by shutouts.
Dreher at Calhoun County: Blue Devils got running game going last week with Washington.
Dutch Fork at River Bluff: Third consecutive road game for Dutch Fork, the top-ranked team in Midlands.
Pick: Dutch Fork
Eau Claire at Lewsiville: Unbeaten Lewisville averaging 430 yards of offense per game.
Fairfield Central at Newberry (Newberry College): Matchup usually a postseason preview.
Gray Collegiate at Pelion: Both teams looking for first win and coming off a bye.
Pick: Gray Collegiate
Laurence Manning at Heathwood Hall: LMA has allowed 14 points or less in its three wins.
Pick: Laurence Manning
Lexington at Spring Valley: Vikings committed seven turnovers last week.
Pick: Spring Valley
Lugoff-Elgin at South Aiken: L-E coming off tough loss to Flora, will face tough test in T-Breds.
Pick: South Aiken
Ninety-Six at Mid-Carolina: Both teams looking for first win.
Orangeburg Prep at Hammond: Hammond looks to start new winning streak.
Richland Northeast at A.C. Flora (Memorial Stadium): Running game, O-line help RNE in this one.
Pick: Richland Northeast
Ridge View at Union County: Blazers looking to go 5-0 heading into bye week.
Pick: Ridge View
Saluda at Batesburg-Leesville: 80th meeting between the programs.
West Florence at Camden: Murphy’s running, Beckley’s passing key for Camden.
White Knoll at North Augusta: NA 2-0 against Georgia teams, 0-1 against SC squads
Pick: North Augusta
Wilson Hall at Cardinal Newman: Last two games decided by seven points or less.
Pick: Cardinal Newman
Last Week: 16-5