Calhoun County (6-2, 2-1) at Batesburg-Leesville (6-2, 3-0)

Radio: 1430 AM

Players to watch – CC: QB Terrence Brunson, LB Kamont’a Howell; B-L: QB Bishop Cannon, DL Zahadrian Burgess

Notes: Batesburg-Leesville is 8-0 all-time against Calhoun with last meeting coming in 1999. … B-L can clinch Region 5-2A title with win over Calhoun this week and Barnwell next week. … Calhoun is coached by former Lower Richland and Dutch Fork coach Bill Kimrey. … B-L held Silver Bluff to 166 yards of offense last week.

Cardinal Newman (3-5, 2-5) at Ben Lippen (6-2, 4-2)

Players to watch – CN: QB Cam Tringali, Liam O’Malley; BL: RB/WR Bryce Thompson, QB Patrick McClure

Notes: Ben Lippen has clinched a spot in next week’s SCISA 3A playoffs. … Ben Lippen racked up 445 yards of offense in last week’s win over Wilson Hall. … Cardinal Newman was off last week. … CN quarterback Cam Tringali is sixth in the Midlands in passing with 1,515 yards.

Chapin (6-2, 3-0) at Airport (3-5, 2-1)

Players to watch – C: WR Xzavion Gordon, QB Cooper Bemis; A: WR/DB Kerryon Richardson, RB/WR CJ Wright

Notes: Airport leads series 3-1 with last meeting coming in 2007. Non-region game for two teams, which have each clinched playoff spots … Airport gave up 572 yards and 70 points in loss to South Aiken last week. … Chapin’s Cam Liles picked off two passes in win over O-W last week. … Xzavion Gordon leads Chapin with 35 catches for 782 yards.

Dreher (5-2, 0-1) at A.C. Flora (4-4, 2-0)

Players to watch – D: RB/LB Jay Washington, RB/DB Anthony Salters; ACF: DB Lane Botkin, QB Carlton Andrews

Notes: A.C. Flora has won nine in a row in series. Dreher’s last win came in 2006. … ACF wins Region 5-4A title with win this week and next week over Chapin. … Flora has won three straight games, averaging 51.3 points per contest. … Dreher running back Jay Washington needs 63 yards for 1,000 yards on the season.

Hammond (7-1, 5-1) at Heathwood Hall (2-6, 1-6)

Players to watch – H: QB Corbett Glick, WR Lucas Prickett; HH: QB Duffy Beal, RB Brandon McCullough

Notes: Hammond wraps first-round bye in playoffs with victory. … Hammond’s margin of victory in its seven victories is 36.8 points. … Heathwood’s Brandon McCullough returned two kicks for touchdowns last week against Orangeburg Prep.

Irmo (3-5, 2-2) at Dutch Fork (8-0, 4-0)

Players to watch – I: RB Jeffrey Tharp, RB Shakeem Bradley; DF: QB Reese Nichols, WR Bobby Irby

Notes: Irmo leads all-time series 17-9 but Dutch Fork has won seven of last eight in series. … Dutch Fork clinches Region 5-5A title tonight with victory. … Led by Jeffrey Tharp (173) and Shakeem Bradley (159), Irmo rushed for 412 yards last week against River Bluff. … Dutch Fork is allowing just 107.5 yards rushing a game and outscored opponents, 218-41, in the first half.

Ridge View (7-1, 2-1) at Lancaster (4-4, 1-2)

Players to watch – RV: DE Damani Staley, QB Jalen Smith; L: RB Ant Foster, QB Jamias Shropshire

Notes: Ridge View leads all-time series 7-5 and has won the last four meetings. … RV will clinch at no worse a top two spot in the region and home playoff game with a win this week and next week against York. … RV’s Damani Staley leads the Midlands with 14 sacks.

Spring Valley (5-3, 2-2) at Blythewood (7-2, 4-1)

Players to watch – SV: QB Quincy Hill, DL/LB Da’ Prince Haynes; B: QB Jordyn Adams, DB Sekwan Jenkins

Notes: Blythewood leads all-time series 7-1. … Regular-season finale for Blythewood, which will have two weeks off before playoffs begin Nov. 18. … Blythewood QB Jordyn Adams needs 120 yards for 2,000 passing yards this season.

Strom Thurmond (5-3, 2-1) at Brookland-Cayce (6-1, 2-0)

Radio: 1600 AM

Players to watch – ST: QB Tyrece Nick, WR/DB Amani Jones; B-C: QB Reed Charpia, DL Octavious Pringle

Notes: Strom Thurmond has won six straight in series with last meeting coming in 2013. … Both teams ranked in this week’s SC Prep Writers 3A poll with B-C at No. 5 and Strom Thurmond No. 6. … B-C can win Region 5-3A title with a win this week and next week against Gilbert. … B-C is looking to win its seventh game, which hasn’t happened since 2004.

Westwood (2-6, 0-3) at Richland Northeast (4-4, 0-3)

Players to watch – W: LB Darieus McCaskill, WR Cortes Braham; RNE: DE Daquan Holley, RB Tyquandre Davis

Notes: Westwood leads series, 3-1. … Both teams are winless in Region 3-4A but still have shot at the playoffs by winning final two regular season games. … Darieus McCaskill leads Westwood with 88 tackles. … RNE allowing 96.8 rushing yards a game.

White Knoll (4-4, 1-3) at Lexington (5-3, 2-2)

Radio: 107.5 FM

Players to watch – WK: RB Maurice Jones, LB Brandon Serio; L: OL Cameron Williams, LB John Mills

Notes: Lexington has won nine of last 10 against White Knoll. … WK and Lexington among four teams in mix for final three guaranteed playoff spots in Region 5-5A. ... WK running back Maurice Jones is 131 yards away from 1,000 yards rushing on season.