Batesburg-Leesville (6-3, 3-1) at Barnwell (8-1, 3-1)

Players to watch – B-L: RB Tyreek Tolen, DL Zhadrian Burgess; B: RB Anton Buxton, RB Mykal Lee

Notes – Batesburg-Leesville leads all-time series 11-1. Series dates back to 1921. … A B-L victory guarantees the Panthers no worse than a second-place finish in region. If the Panthers lose and Calhoun County defeats B-E, they will finish third. …. Barnwell is averaging 320 yards a game on the ground.

Chapin (7-2, 3-0) at A.C. Flora (5-4, 3-0) at Spirit Communications Park

Players to watch – WR Xzavion Gordon, TE Will Register; ACF: DB/ATH Lane Botkin, WR Garrett Whetstone

Notes – Game played at Spirit Communications Park, home of Columbia Fireflies. Winner of game wins Region 5-4A and clinches homefield through playoffs up until state title game. … Series is tied 3-3 with Flora winning 28-27 last year. … A.C. Flora averages 346 yards per game on offense, and Chapin averages 345.

Dutch Fork (9-0, 5-0) at Lexington (5-4, 2-3)

Players to watch – DF: QB Reese Nichols, WR Bobby Irby; L: OL Cameron Williams, RB Jordan Hiller

Notes – Dutch Fork secures first unbeaten regular season with a victory. … Teams have split their last eight meetings against each other. … Dutch Fork QB Reese Nichols has rushed for more than 100 yards in each of the last two games, and RB Ron Hoff has four straight 100-yard games. … Lexington’s Jordan Hiller rushed for 206 yards last week against White Knoll in first game as a starter. Hiller replaced Daquan Wells (violation of team rules), who is no longer with team.

Fairfield Central (7-2, 3-0) at Camden (5-4, 2-1)

TV/ WACH Fox 57.2/Time Warner 1250 and www.wach.com

Players to watch – FC: Stanley McManus, LB Darryl Camack; C: QB Devin Beckley, WR Jo Jo Watson

Notes – Fairfield Central clinches fifth straight region title with victory. If Camden wins, it will finish in three-way with FC and Chester or will win region outright if Chester loses to Columbia. … FC leads series 6-2 with last meeting coming in 2007. … Camden is averaging 427 yards per game on offense. … FC has won five straight games and is giving up just 11.6 points a game during the winning streak.

Gilbert (9-0, 4-0) at Brookland-Cayce (7-1, 3-0)

Radio: 107.5 FM/1600 AM

Players to watch – G: QB Josh Strickland, RB Catriez Cook; B-C: DL Tay Pringle, QB Reed Charpia

Notes – Winner of game clinches Region 5-3A championship. Gilbert has never won a region title in 44-year history of school while B-C’s last region title came in 2003. … If Gilbert wins, it also will clinch first perfect regular season in school history. … All-time series between two teams is tied 3-3. … Gilbert’s Dylan McNatt leads Midlands with six interceptions. … Three B-C players, Sammy Lykes, Quinten Hook and Dominick Perry, each have four interceptions apiece.

Gray Collegiate (4-5, 3-1) at Saluda (8-1, 4-0)

Players to watch – GCA: QB Bryce Fields, WR Chylon Thomas; S: Malik Brooks;

Notes – Saluda clinches Region 3-2A with a victory. A GCA victory would make a three-way tie in the region. … Saluda is averaging 45 points a game over its last five games. … GCA quarterback Bryce Fields is second in Midlands with 2,261 yards and 24 TDs.

Irmo (3-6, 2-3) at Spring Valley (6-3, 3-2)

Players to watch – I: RB Jeffrey Tharp, OL Nick Comfort; SV: LB Channing Tindall, RB Terrell Jackson

Notes – Spring Valley clinches No. 2 spot in Region 5-5A and first-round playoff game with victory. Irmo clinches playoff spot with win but still might earn an at-large playoff spot with loss. … Irmo has won six of last nine in series including last year’s 21-20 victory. … SV averages 258 yards rushing per game, while Irmo is at 235.1 per game

North Augusta (6-3, 2-1) at Airport (3-6, 2-1)

Players to watch – NA: QB Landon Washington, Tre Lawson; A: QB Brett Burnett, WR/DB Kerryon Richardson.

Notes – Winner of game finishes second in Region 4-4A and get a home playoff game in the first round. … Airport QB Brett Burnett threw for school-record 400 yards and 4 TDs last week against Chapin. … Jamir Robinson leads Airport with 819 yards rushing.

River Bluff (1-8, 0-5) at White Knoll (5-4, 2-3)

Players to watch – RB: Stephen Kight, WR/DB DJ Ledell; WK: RB Maurice Jones, LB Joe Beckett

Notes – White Knoll clinches playoff spot with victory. … Final game for River Bluff coach David Bennett, who became Director of Athletics for Lexington One. … River Bluff has thrown just two TD passes this season. … WK’s Maurice Jones went over 1,000-yards rushing last week for the second straight year.

Wilson Hall (5-4) at Ben Lippen (6-2)

Players to watch – WH: RB Justin Timmons, TE/LB Mitchell Matthews; BL: QB Patrick McClure, WR/RB Bryce Thompson

Notes – First-round SCISA 3A playoff game. Winner plays at Hammond next week. … Ben Lippen defeated Wilson Hall 41-8 on Oct. 21. … Ben Lippen has scored 127 points in the first quarter this season. … Ben Lippen QB Patrick McClure accounted for five TDs last week against Cardinal Newman.

York (4-5, 3-1) at Ridge View (8-1, 3-1)

Players to watch – Y: QB Ethan Mitchell, RB Paul Moore; RV: RB/DB Latheron Rogers-Anderson, DE Damani Staley

Notes – Winner of game clinches No. 2 spot in Region 3-4A and earns home playoff game. … Ridge View’s Damani Staley is three sacks away from tying his school-record of 21 he set last season. … RV’s Latheron Rogers-Anderson has rushed for 359 yards over the past two weeks.