USC Gamecocks Football

First look at South Carolina-Kentucky: Betting odds, TV details, more

South Carolina and edge rusher Dylan Stewart (6) host the Kentucky Wildcats this weekend.
South Carolina and edge rusher Dylan Stewart (6) host the Kentucky Wildcats this weekend. bsimms@herald-leader.com

Following a 29-20 loss to Missouri in the other Columbia, South Carolina football returns home for a fourth-straight night game against the Kentucky Wildcats.

Here’s everything you need to know as the Gamecocks seek to bounce back from an 0-2 start in the SEC:

How to watch South Carolina vs. Kentucky

When: Saturday, Sept. 27 at 7:45 p.m.

Where: Williams-Brice Stadium

TV/stream: SEC Network and the ESPN app

Series history: The Gamecocks are 21-14-1 against Kentucky all-time, including three consecutive wins against the Wildcats since 2022. USC won the matchup 31-6 last season in Lexington.

Betting odds

South Carolina is a 3.5-point favorite/underdog against Kentucky, according to the VegasInsider consensus line that factors in multiple sportsbooks. The over/under is set at 45.5 points.

About South Carolina

The Gamecocks are now 2-2 (0-2 SEC) after a 29-20 loss against the Missouri Tigers in USC’s first conference road game of the season. USC’s defense gave up 285 yards rushing and two touchdowns in a slow-burning collapse in the fourth quarter. South Carolina started the year 2-0 before taking on Vanderbilt at home in the SEC opener and losing 31-7. Against the Commodores, USC struggled to get going on offense, particularly after LaNorris Sellers went out of the game with an injury, and after the team had multiple defensive lapses.

About Kentucky

The Wildcats are coming off of an open week and are 2-1 (0-1 SEC) to start the season. The trip to Williams-Brice Stadium will be the first road game for Kentucky this season. After a 24-16 win against Toledo to kick off the year, the Wildcats well just short to Ole Miss 30-23. Kentucky settled for a field goal with just over a minute left in the game, and the Rebels ran out the clock. The Wildcats bounced back in Week 3 with a 48-23 win against Eastern Michigan.

South Carolina Gamecocks quarterback LaNorris Sellers (16) gets off a pass in front of Kentucky Wildcats linebacker Daveren Rayner (17) during their 2024 football game at Kroger Field in Lexington, Kentucky.
South Carolina Gamecocks quarterback LaNorris Sellers (16) gets off a pass in front of Kentucky Wildcats linebacker Daveren Rayner (17) during their 2024 football game at Kroger Field in Lexington, Kentucky. David Rearic

Players to watch: Gamecocks and Wildcats

South Carolina

LaNorris Sellers, QB: Sellers came back from injury and looked comfortable against the Tigers. He completed 18 passes for 302 yards and two touchdowns, but also had 10 rushes for minus-28 yards. He’ll need his offensive line and running backs to boost the run game if those passing numbers will convert to wins in the future.

Vicari Swain, DB: Swain’s historic special teams play hasn’t limited his production on defense. He’s arguably the Gamecocks’ best tackler and has been solid in pass coverage as well. He finished the Mizzou game with 10 tackles (eight solo), a tackle for loss and a pass breakup.

Kentucky

Cutter Boley, QB: Boley, a redshirt freshman, started the season as the backup to Texas A&M and Incarnate Word transfer Zach Calzada. But after the fifth-year senior was pulled mid-game against Ole Miss due to a shoulder injury, Boley took over and remained the starter against Eastern Michigan. He threw for 240 yards and two touchdowns on 12 attempts against the Eagles. Boley is likely to get the start against USC.

Mi’Quise Humphrey-Grace, DL: Humphrey-Grace left midway through Kentucky’s season opener against Toledo and was seen in a walking boot on the sideline. However, he was active against Ole Miss and has recorded four tackles in each of the last two games. The junior transfer from South Dakota picked up his first sack of the year against Eastern Michigan. With a week of rest to get fully healthy, he could make an impact against USC’s struggling offensive line.

South Carolina 2025 football schedule

  • Aug. 31: USC 24, Virginia Tech 11
  • Sept. 6: USC 38, SC State 10
  • Sept. 13: Vanderbilt 31, USC 7
  • Sept. 20: Missouri 29, USC 20
  • Sept. 27 vs. Kentucky - 7:45 p.m. (SEC Network)
  • Oct. 11 at LSU - TBD
  • Oct. 18 vs. Oklahoma - TBD
  • Oct. 25 vs. Alabama - TBD
  • Nov. 1 at Ole Miss - TBD
  • Nov. 15 at Texas A&M - TBD
  • Nov. 22 vs. Coastal Carolina - TBD
  • Nov. 29 vs. Clemson - Noon (ABC or ESPN)
Jackson Castellano
The State
Jackson Castellano is a former journalist for The State
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