First look at South Carolina vs. No. 7 Ole Miss: Betting odds, TV details, more
After falling short of a massive upset in a 29-22 loss against then-No. 4 Alabama last weekend, South Carolina has the chance for arguably a bigger upset this Saturday: A trip to Oxford, Mississippi for a battle against No. 7 Ole Miss.
Here’s what you need to know about USC’s next game:
How to watch South Carolina vs. No. 7 Ole Miss
When: 7 p.m. Saturday
Where: Vaught-Hemingway Stadium (Oxford, Mississippi)
TV/stream: ESPN
Series history: South Carolina is 8-10 against the Rebels since the first matchup in 1947. Ole Miss holds a two-game winning streak against the Gamecocks, with a 59-42 victory in 2020 and a 27-3 win last season. This season’s game marks the first time the two programs have faced each other in consecutive years since 2008-09.
Betting odds
USC is a 12.5-point underdog against Ole Miss, according to the VegasInsider consensus line that factors in multiple sportsbooks. The over/under is 52.5 points.
About South Carolina
The Gamecocks nearly added a significant bright spot to an overall disappointing season against the Crimson Tide. USC led going into the fourth quarter and found itself on offense with 2:16 on the clock and a tie game. The upset dream died seconds later as quarterback LaNorris Sellers fumbled and opened the door for Alabama’s game-winning touchdown. USC is now 3-5 (1-5 in the SEC) and on the edge of missing a bowl game.
About Ole Miss
Ole Miss has fared much better than USC this year. Headed by quarterback Trinidad Chambliss and head coach Lane Kiffin, the Rebels are 7-1 overall and 3-1 in the SEC, with high aspirations for a spot in the College Football Playoff. Ole Miss’ one loss came on the road against Georgia. The Bulldogs rallied behind QB Gunnar Stockton’s four touchdowns to win 43-35. Ole Miss bounced back last weekend in Norman, Oklahoma in a 34-26 win against Brent Venables and the Sooners.
Players to watch: Gamecocks and Rebels
South Carolina
Jayden Sellers, WR: The brother of USC’s star QB, Sellers has made his own name in the past few weeks. He led the team with six receptions and 57 receiving yards against Oklahoma and earned a starting spot against Alabama. He recorded three catches for 38 yards against the Tide, including a key 22-yard reception that set up a penalty-negated touchdown and an eventual field goal. Sellers should get another chance at quality snaps against the Rebels.
Peyton Williams, DB: Beamer credited his defensive front for a standout performance against Alabama, but Williams quietly shut down the Tide’s passing offense. He finished with a team-high six solo tackles and two pass breakups. USC’s secondary has been banged up all year and is still getting back into a regular flow. Williams was a big factor in the group’s progress against Alabama.
Ole Miss
Trinidad Chambliss, QB: Chambliss has been one of college football’s best stories this season. A transfer from Division II Ferris State, he came in for starting QB Austin Simmons in Week 3 against Arkansas and has held the job ever since. Chambliss is up to 1,549 passing yards and eight touchdowns with just one interception. He threw for 315 yards against Oklahoma. There’s no QB controversy in Oxford — Chambliss will lead the Ole Miss offense against USC.
TJ Dottery, LB: Dottery has been a force as Ole Miss’ leading tackler this season, and the junior once again led his team with six tackles against Oklahoma. He’ll have his hands full trying to contain Sellers through the air and on the ground, but expect him to finish the game atop the box score once again.
South Carolina 2025 football schedule
- Aug. 31: South Carolina 24, Virginia Tech 11
- Sept. 6: USC 38, SC State 10
- Sept. 13: Vanderbilt 31, USC 7
- Sept. 20: Missouri 29, USC 20
- Sept. 27: USC 35, Kentucky 13
- Oct. 11: LSU 20, USC 10
- Oct. 18: Oklahoma 26, USC 7
- Oct. 25: Alabama 29, USC 22
- Nov. 1 at Ole Miss - 7:00 p.m. ET (ESPN)
- Nov. 15 at Texas A&M - TBD
- Nov. 22 vs. Coastal Carolina - TBD
- Nov. 29 vs. Clemson - Noon (ABC or ESPN)
