Carolina Panthers running back Christian McCaffrey is Sunday’s gamechanger against the Philadelphia Eagles. Running McCaffrey more consistently will open up more deep play-action passes for quarterback Cam Newton and the offense.
Emmanuel Sanders threw and caught touchdown passes, Denver returned two interceptions for first-quarter touchdowns and the Broncos snapped a four-game losing streak with a 45-10 rout of the Arizona Cardinals.
The New Orleans Saints did not waste any time getting Mark Ingram back in the fold after a four-game suspension for violating the NFL's policy on performance-enhancing substances as the running back carried the ball 16 times for 53 yards and two touchdowns in the team's 43-19 thrashing of the Washington Redskins on Oct. 8.
Philadelphia Eagles running back Darren Sproles will miss his sixth straight game because of a hamstring injury, and cornerback Sidney Jones and safety Corey Graham are also out for Sunday's game against Carolina.